Estrogen sensitive liver transgenic zebrafish (Danio rerio) line (Tg(vtg1:mCherry)) suitable for the direct detection of estrogenicity in environmental samples
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چکیده
منابع مشابه
Liver development in zebrafish (Danio rerio).
Liver is one of the largest internal organs in the body and its importance for metabolism, detoxification and homeostasis has been well established. In this review, we summarized recent progresses in studying liver initiation and development during embryogenesis using zebrafish as a model system. We mainly focused on topics related to the specification of hepatoblasts from endoderm, the formati...
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The zebrafish has long been a favourite model for the study of vertebrate development. Here we provide an overview of the current state of knowledge and resources for the study of this fish, with comments on the future direction of zebrafish genomics from Professor Mark Fishman and Dr Stephen Wilson.
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Low temperatures may cause severe growth inhibition and mortality in fish. In order to understand the mechanism of cold tolerance, a transgenic zebrafish Tg (smyd1:m3ck) model was established to study the effect of energy homeostasis during cold stress. The muscle-specific promoter Smyd1 was used to express the carp muscle form III of creatine kinase (M3-CK), which maintained enzymatic activity...
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The zebrafish embryo test is a widely used bioassay for the testing of chemicals, effluents and other types of environmental samples. Oxygen depletion in the testing of sediments and effluents is especially important and may be a confounding factor in the interpretation of apparent toxicity. In order to identify oxygen levels critical to early developmental stages of zebrafish, oxygen consumpti...
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Zebrafish, Danio rerio (Hamilton), is one of the most important vertebrate model organism in genetics, developmental biology, neurophysiology and biomedicine (Rubinstein, 2003; Amsterdam and Hopkins, 2006). It is a small, robust fish, so large numbers can be kept easily and cheaply in the laboratory, where it breeds all year round. Development is rapid, with precursors to all major organs devel...
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ژورنال
عنوان ژورنال: Aquatic Toxicology
سال: 2019
ISSN: 0166-445X
DOI: 10.1016/j.aquatox.2019.01.008